Such scaffolds usually have different pore geometries (e.g. Porous scaffolds are commonly used for housing the cells in a three-dimensional (3D) culturing environment. Mechanobiological studies in vitro apply a dynamic micro-mechanical environment to cells via bioreactors. It will have implications for studying bone physiology and pathology and to guide the strategy for regenerating both the structural and functional features of bone. Mechanobiology research is for understanding the role of mechanics in cell physiology and pathology. 4School of System Design and Intelligent Manufacturing, Southern University of Science and Technology, Shenzhen, China.3Zienkiewicz Centre for Computational Engineering, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom.2Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, Eindhoven, Netherlands.1Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Feihu Zhao 1,2,3 Yi Xiong 4 Keita Ito 1,2 Bert van Rietbergen 1 Sandra Hofmann 1,2*
